South America - Top 100+ Cities by Population

Population data by city is the population of the city itself, not the metro area (for specific metro area data, see our ranking by metro area). Data is as of 2011 estimates.

Rank CityCountryPopulation
3,447. Santo Pipó Argentina 5,447
1,284. Santo Estêvão Brazil 27,279
223. Santo Domingo de los Colorados Ecuador 200,421
4,042. Santo Domingo Colombia 2,873
2,684. Santo Augusto Brazil 10,305
2,901. Santo Antônio do Tauá Brazil 8,921
2,490. Santo Antônio do Sudoeste Brazil 11,723
1,504. Santo Antônio do Monte Brazil 22,592
3,285. Santo Antônio do Leverger Brazil 6,387
2,838. Santo Antônio do Içá Brazil 9,302
1,895. Santo Antônio do Amparo Brazil 16,730
1,788. Santo Antônio de Posse Brazil 18,148
1,096. Santo Antônio de Pádua Brazil 33,076
553. Santo Antônio de Jesus Brazil 73,957
1,034. Santo Antônio da Platina Brazil 35,260
2,368. Santo Antônio Brazil 12,529
615. Santo Ângelo Brazil 64,606
55. Santo André Brazil 662,373
1,850. Santo Anastácio Brazil 17,233
2,839. Santo Amaro das Brotas Brazil 9,302
1,756. Santo Amaro da Imperatriz Brazil 18,418
831. Santo Amaro Brazil 46,748
4,490. Santiago Vázquez Uruguay 1,468
4,195. Santiago Temple Argentina 2,358
2,016. Santiago del Torno Bolivia 15,543
108. Santiago del Estero Argentina 354,692
3,227. Santiago de Chuco Peru 6,759
1,539. Santiago de Cao Peru 21,982
2,658. Santiago Peru 10,449
4,264. Santiago Paraguay 2,144
4,085. Santiago Colombia 2,715
4,659. Santiago Colombia 1,032
6. Santiago Chile 4,837,295
836. Santiago Brazil 46,611
236. Santarém Brazil 189,047
933. Santander de Quilichao Colombia 40,798
1,362. Santana do Paraíso Brazil 25,515
3,269. Santana do Mundaú Brazil 6,439
3,015. Santana do Matos Brazil 8,050
455. Santana do Livramento Brazil 89,694
1,337. Santana do Ipanema Brazil 26,146
2,096. Santana do Acaraú Brazil 14,707
415. Santana de Parnaíba Brazil 98,989
4,290. Santana Colombia 2,091
496. Santana Brazil 83,927
2,350. Santana Brazil 12,628
1,401. Santaluz Brazil 24,739
4,162. Santacruz Colombia 2,469
1,265. Santa Vitória do Palmar Brazil 27,775
2,495. Santa Vitória Brazil 11,656
156. Santa Teresa Venezuela 278,890
2,859. Santa Teresa Brazil 9,156
2,884. Santa Sylvina Argentina 9,040
4,646. Santa Sofía Colombia 1,058
2,902. Santa Rosa del Sur Colombia 8,904
3,646. Santa Rosa del Conlara Argentina 4,489
3,197. Santa Rosa de Viterbo Colombia 6,923
1,564. Santa Rosa de Viterbo Brazil 21,473
4,315. Santa Rosa de Tastil Argentina 2,000
3,224. Santa Rosa de Río Primero Argentina 6,788
2,704. Santa Rosa de Osos Colombia 10,191
2,804. Santa Rosa de Calamuchita Argentina 9,504
678. Santa Rosa de Cabal Colombia 57,928
3,845. Santa Rosa Uruguay 3,711
2,637. Santa Rosa Peru 10,625
3,142. Santa Rosa Paraguay 7,257
910. Santa Rosa Ecuador 41,816
2,639. Santa Rosa Colombia 10,604
666. Santa Rosa Brazil 58,957
3,652. Santa Rosa Bolivia 4,459
372. Santa Rosa Argentina 111,424
2,977. Santa Rosa Argentina 8,330
1,222. Santa Rita do Sapucaí Brazil 28,765
1,410. Santa Rita do Passa Quatro Brazil 24,578
1,136. Santa Rita Venezuela 31,810
2,473. Santa Rita Paraguay 11,823
349. Santa Rita Brazil 119,893
2,277. Santa Rita Brazil 13,224
4,166. Santa Rita Bolivia 2,444
1,858. Santa Quitéria do Maranhão Brazil 17,174
1,419. Santa Quitéria Brazil 24,391
3,510. Santa Monica Brazil 5,100
84. Santa Marta Colombia 431,781
2,744. Santa Maria do Suaçuí Brazil 9,936
2,307. Santa Maria do Pará Brazil 12,915
1,457. Santa Maria da Vitória Brazil 23,488
2,098. Santa Maria da Boa Vista Brazil 14,695
2,082. Santa Maria Peru 14,853
4,288. Santa María Paraguay 2,095
4,073. Santa María Colombia 2,761
4,233. Santa María Colombia 2,238
180. Santa Maria Brazil 249,219
4,406. Santa María Argentina 1,687
3,754. Santa Magdalena Argentina 4,059
186. Santa Luzia Brazil 243,503
1,484. Santa Luzia Brazil 22,909
2,274. Santa Luzia Brazil 13,243
1,921. Santa Lucía Uruguay 16,438
3,687. Santa Lucía Peru 4,320
2,369. Santa Lucía Ecuador 12,523